Cytotoxicity of Doxycycline Effluent Generated by the Fenton Process

Alexandre Augusto Borghi; Laura Oliveira-Nascimento; Marco Antônio Stephano; Paula Monteiro de Souza; Attilio Converti; Mauri Sérgio Alves Palma

doi:10.1155/2014/439461

The Scientific World Journal (Jan 2014)

Cytotoxicity of Doxycycline Effluent Generated by the Fenton Process

Alexandre Augusto Borghi,
Laura Oliveira-Nascimento,
Marco Antônio Stephano,
Paula Monteiro de Souza,
Attilio Converti,
Mauri Sérgio Alves Palma

Affiliations

Alexandre Augusto Borghi: Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, Bloco 16, Avenida Prof. Lineu Prestes 580, 05508-900 São Paulo, SP, Brazil
Laura Oliveira-Nascimento: Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, University Town Zeferino Vaz, Rua Monteiro Lobato 255, 13083-862 Campinas, SP, Brazil
Marco Antônio Stephano: Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, Bloco 16, Avenida Prof. Lineu Prestes 580, 05508-900 São Paulo, SP, Brazil
Paula Monteiro de Souza: Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, Bloco 16, Avenida Prof. Lineu Prestes 580, 05508-900 São Paulo, SP, Brazil
Attilio Converti: Department of Civil, Chemical and Environmental Engineering, Pole of Chemical Engineering, Genoa University, Via Opera Pia 15, 16145 Genoa, Italy
Mauri Sérgio Alves Palma: Department of Biochemical and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of São Paulo, Bloco 16, Avenida Prof. Lineu Prestes 580, 05508-900 São Paulo, SP, Brazil

DOI: https://doi.org/10.1155/2014/439461
Journal volume & issue: Vol. 2014

Abstract

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This study aims at determining the Minimum Inhibitory Concentration with Escherichia coli ATCC 25922 and cytotoxicity to L929 cells (ATCC CCL-1) of the waste generated by doxycycline degradation by the Fenton process. This process has shown promise in this treatment thanks mainly to the fact that the waste did not show any relevant inhibitory effect on the test organism and no cytotoxicity to L-929 cells, thus demonstrating that the antibiotic properties were inactivated.

Published in The Scientific World Journal

ISSN: 2356-6140 (Print); 1537-744X (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Technology; Medicine; Science
Website: https://onlinelibrary.wiley.com/journal/8086

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