Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China
Kaiyan He
Changping Laboratory, Beijing 102206, PR China
Congcong Li
Changping Laboratory, Beijing 102206, PR China
Xiao Ma
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China; Beijing City Key Lab for Medical Physics and Engineering, Institution of Heavy lon Physics, School of Physics, Peking University, Beijing 100871, PR China
Fufu Zheng
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China; Beijing City Key Lab for Medical Physics and Engineering, Institution of Heavy lon Physics, School of Physics, Peking University, Beijing 100871, PR China
Wei Xu
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China
Pan Liao
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China
Rui Yang
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China; Beijing City Key Lab for Medical Physics and Engineering, Institution of Heavy lon Physics, School of Physics, Peking University, Beijing 100871, PR China
Dongxu Li
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China; Beijing City Key Lab for Medical Physics and Engineering, Institution of Heavy lon Physics, School of Physics, Peking University, Beijing 100871, PR China
Lang Qin
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China
Shuai Na
National Biomedical Imaging Center, Peking University, Beijing 100871, PR China
Center for MRl Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, PR China; Changping Laboratory, Beijing 102206, PR China; Beijing City Key Lab for Medical Physics and Engineering, Institution of Heavy lon Physics, School of Physics, Peking University, Beijing 100871, PR China; PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing 100871, China; National Biomedical Imaging Center, Peking University, Beijing 100871, PR China; Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei 230088, PR China; Corresponding authors.
The current magnetoencephalography (MEG) systems, which rely on cables for control and signal transmission, do not fully realize the potential of wearable optically pumped magnetometers (OPM). This study presents a significant advancement in wireless OPM-MEG by reducing magnetization in the electronics and developing a tailored wireless communication protocol. Our protocol effectively eliminates electromagnetic interference, particularly in the critical frequency bands of MEG signals, and accurately synchronizes the acquisition and stimulation channels with the host computer's clock. We have successfully achieved single-channel wireless OPM-MEG measurement and demonstrated its reliability by replicating three well-established experiments: The alpha rhythm, auditory evoked field, and steady-state visual evoked field in the human brain. Our prototype wireless OPM-MEG system not only streamlines the measurement process but also represents a major step forward in the development of wearable OPM-MEG applications in both neuroscience and clinical research.
