Nature Communications (Feb 2021)

Genome-wide fine-mapping identifies pleiotropic and functional variants that predict many traits across global cattle populations

  • Ruidong Xiang,
  • Iona M. MacLeod,
  • Hans D. Daetwyler,
  • Gerben de Jong,
  • Erin O’Connor,
  • Chris Schrooten,
  • Amanda J. Chamberlain,
  • Michael E. Goddard

DOI
https://doi.org/10.1038/s41467-021-21001-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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Genomic prediction of phenotype may be improved by using DNA mutations with functional, evolutionary, and pleiotropic consequences. Here the authors describe a method for genome-wide fine-mapping of QTLs and develop a genotyping array for improved prediction of genetic values for cattle traits.