Two Contradictory Fates Following a Similar Malignancy: Is Prognosis Predictable in Borderline Ovarian Tumors?

Abstract

Background: Borderline ovarian tumors make a small contribution to the ovarian pathologies; however, with regard to the prevalence of this malignancy at reproductive age, prognosis and standard treatment of these patients are of great significance in oncology trials. The present study aimed to introduce two patients with borderline ovarian tumors to examine the prognosis determinants based on similar studies. Case Report: In the winter of 2018, two patients with similar medical history of ovarian cysts diagnosed in 2016 with stage I epithelial ovarian tumor (borderline) pathology referred to an emergency department in a university hospital. The first patient was a 29-year-old woman. Following the surgery to preserve her fertility, the mentioned patient experienced relapse and metastases without any proper responses to treatment. Despite all the efforts of the medical team, the patient died due to the severity of her disease. The other patient was a 26-year-old woman, who was admitted at 36th week of pregnancy with the diagnosis of preeclampsia, and delivered a 2800-gram healthy boy. Conclusion: Although it seems that borderline tumor is distinct from other ovarian malignancies in term of prognosis, based on the present case report, the prognosis must be investigated in each patient in individualize manner.

Keywords

• Ovary
• Tumors
• Fertility preservation
• Genetic testing
• Markers
• Tumor
• Prognosis