Carvedilol dihydrogen phosphate hemihydrate: a powder study

Abstract

In the cation of the title compound [systematic name: 3-(9H-carbazol-4-yloxy)-2-hydroxy-N-[2-(2-methoxyphenoxy)ethyl]propan-1-aminium dihydrogen phosphate hemihydrate], C24H27N2O4+·H2PO4−·0.5H2O, the mean planes of the tricyclic ring system and the benzene ring form a dihedral angle of 87.2 (2)°. In the crystal structure, the solvent water molecule is situated on a twofold rotation axis linking two cations via O—H...O and N—H...O hydrogen bonds. The anions contribute to the formation O—H...O and N—H...O hydrogen bonds between the anions and cations, which consolidate the crystal packing.