Curcumin in chronic lymphocytic leukemia – A review

Abstract

Curcumin is a widely researched natural product and is known to possess anti-carcinogenic properties. Chronic lymphocytic leukemia is a type of leukemia that principally affects patients with age higher than 60 years. Since the toxicity of conventional drugs exceeds the benefits of treating this leukemia type, patients are treated only in the advanced symptomatic stages. The current article reviews curcumin, its general actions and targets in cancer, and specifically that of it in chronic lymphocytic leukemia.

Keywords

• Curcumin
• Chronic lymphocytic leukemia
• Nuclear factor kappa B
• STAT3
• Akt
• Apoptosis