A Study on Clinico Radiological Profile and Treatment Pattern of Patients Admitted with Mucormycosis in a Teaching Institution

Abstract

Objectives: (1) Primary objective: To study the selected risk factors and clinical and radiological profiles of patients admitted with mucormycosis. (2) Secondary objective: To study the treatment pattern of patients admitted with mucormycosis. Materials and Methods: A descriptive cross-sectional study was conducted, which included the data of all patients admitted with the histopathological diagnosis of mucormycosis after undergoing surgery in the Otorhinolaryngology Department, Government Medical College, Thrissur, from January 2020 to September 2021. The risk factors, clinical and radiological profiles along with the treatment pattern of patients admitted with mucormycosis were analyzed. Results: Most of the cases belonged to the 40–50 age group, although the mean age was 52.24 with patients ranging from the age of 32–76. The male: female ratio was 2:1. All patients had diabetes mellitus. 89.7% had hypertension, and 76.9% had chronic kidney disease. Conclusion: Diabetes mellitus and COVID-19 cause a predilection for mucor to invade the paranasal sinuses and beyond. Aggressive treatment with amphotericin B along with surgical clearance aided by radiological investigation will help in decreasing the morbidity of the disease.

Keywords

• black turbinate sign
• covid-19
• covid-19-associated mucormycosis
• invasive fungal sinusitis
• modified denker’s approach
• mucormycosis