Insulin and IGF-1 in goat milk: influence of the diet

Abstract

Plasma IGF-1 and insulin have both growth-related and anabolic actions. The anabolic role of plasma IGF-1 consists of stimulating the uptake of amino acids and glucose by the cells, with an action similar to that of insulin. The main regulation of plasma IGF-1 and insulin is associated with food intake, especially with energy and protein intake. Moreover, insulin modulates peripheral satiety signals and directly targets the central nervous system to inhibit food intake (Sparks et al., 2003; Gale et al., 2004).

Keywords

• milk insulin, milk IGF-1, goat, bioactive peptides