Congenital Pulmonary Airway Malformation Associated With Papillary Adenocarcinoma

Courtney Breckenfelder, BS; Catherine C. Dawson-Gore, MD, MS; Csaba Galambos, MD, PhD; Kristine S. Corkum, MD; David Partrick, MD; S. Christopher Derderian, MD

Annals of Thoracic Surgery Short Reports (Sep 2024)

Congenital Pulmonary Airway Malformation Associated With Papillary Adenocarcinoma

Courtney Breckenfelder, BS,
Catherine C. Dawson-Gore, MD, MS,
Csaba Galambos, MD, PhD,
Kristine S. Corkum, MD,
David Partrick, MD,
S. Christopher Derderian, MD

Affiliations

Courtney Breckenfelder, BS: Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
Catherine C. Dawson-Gore, MD, MS: Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
Csaba Galambos, MD, PhD: Department of Pathology, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado
Kristine S. Corkum, MD: Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado; Division of Pediatric Surgery, Department of Surgery, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado
David Partrick, MD: Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado; Division of Pediatric Surgery, Department of Surgery, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado
S. Christopher Derderian, MD: Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado; Division of Pediatric Surgery, Department of Surgery, University of Colorado School of Medicine and Children’s Hospital Colorado, Aurora, Colorado; Address correspondence to Dr Derderian, Division of Pediatric Surgery, Children’s Hospital Colorado, 13123 E 16th Ave, Box 323, Aurora, CO 80045.

Journal volume & issue: Vol. 2, no. 3
pp. 400 – 403

Abstract

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Congenital pulmonary airway malformations (CPAMs) are cystic lung lesions often detected prenatally. Resection is often recommended for potential recurrent infections and malignancy. This report describes a case of a 14-year-old female patient who presented with abdominal pain. A computed tomographic scan of the abdomen revealed a cystic lesion at the base of her right lung. Consequently, a computed tomographic arteriogram of the chest demonstrated a right lower lobe lesion concerning for type I CPAM. After thoracoscopic segmentectomy, histopathologic examination revealed papillary adenocarcinoma with a KRAS mutation. Residual CPAM prompted a lobectomy, emphasizing the importance of surgical intervention for cystic lesions.

Published in Annals of Thoracic Surgery Short Reports

ISSN: 2772-9931 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Surgery; Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.sciencedirect.com/journal/annals-of-thoracic-surgery-short-reports

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