Role of human microbiota in the development of colorectal cancer

Abstract

This literature review analyzes the role of human microbiome in cancer development. We provide the data on the most common bacteria found in patients with colon cancer: Fusobacterium nucleatum, Bacteroidеs fragilis, and some strains of Escherichia coli. Fecal microbiota transplantation is a new experimental method of introducing healthy bacterial flora into a recipient with intestinal diseases. The identification of oncogenic bacterial strains will significantly enhance our ability to diagnose and prevent colorectal cancer.

Keywords

• colorectal cancer
• inflammatory bowel disease
• microbiome
• fecal microbiota transplantation