Frontiers in Chemistry (May 2024)

Five years of advances in electrochemical analysis of protein biomarkers in lung cancer: a systematic review

  • Matías Regiart,
  • Martín A. Fernández-Baldo,
  • Bernardino Alcázar Navarrete,
  • Bernardino Alcázar Navarrete,
  • Bernardino Alcázar Navarrete,
  • Concepción Morales García,
  • Concepción Morales García,
  • Beatriz Gómez,
  • Beatriz Gómez,
  • Gonzalo R. Tortella,
  • Gonzalo R. Tortella,
  • Teresa Valero,
  • Teresa Valero,
  • Francisco Gabriel Ortega,
  • Francisco Gabriel Ortega,
  • Francisco Gabriel Ortega,
  • Francisco Gabriel Ortega

DOI
https://doi.org/10.3389/fchem.2024.1390050
Journal volume & issue
Vol. 12

Abstract

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Lung cancer is the leading cause of cancer death in both men and women. It represents a public health problem that must be addressed through the early detection of specific biomarkers and effective treatment. To address this critical issue, it is imperative to implement effective methodologies for specific biomarker detection of lung cancer in real clinical samples. Electrochemical methods, including microfluidic devices and biosensors, can obtain robust results that reduce time, cost, and assay complexity. This comprehensive review will explore specific studies, methodologies, and detection limits and contribute to the depth of the discussion, making it a valuable resource for researchers and clinicians interested in lung cancer diagnosis.

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