Iatrogenic Osteoporosis

Abstract

The literature review provides information on the major calcium-regulating hormones and their role in the regulation of bone remodeling. These processes are also influenced by sex steroids, growth hormone, insulin, cortisol, thyroid hormones and various local growth factors. In this regard, osteopenia and osteoporosis are closely linked to a number of endocrine diseases, some of which are common (diabetes mellitus, hyperthyroidism), others — quite rare (endogenous hypercortisolism). Osteoporosis associated with diabetes, steroid osteoporosis, osteoporosis in thyroid function abnormality are considered in detail. It is emphasized that timely diagnosis and adequate treatment of endocrine diseases associated with a decrease in bone mineral density, contribute to slowing or stopping bone loss, normalization of bone remodeling, enables to reduce the incidence of fractures and to improve the quality of life of the patient.

Keywords

• osteoporosis
• risk factors