Prognostic Factors in the Survival Rate of Patients with Differentiated Thyroid Cancer

Abstract

Background: Thyroid cancer is the most prevalent malignancy of the endocrine systemcancers. Thyroid cancer has increased faster thatn any other malignancy in recent years. Tyroid cancer has different histopathologic types, of which the most common is the differentiated type. Different factors can affect the prognosis of the patients. In this study, we investigated different factors that can affect the prognosis of these patients. Materials and Methods: Thirty-four patients underwent the standard surgery including partial and total thyroidectomy and subsequently received 131I radioiodine 4-6 weeks after surgery. We evaluated the effects of different prognostic factors which can effect on the patients’ survival including age, gender, family history of any malignancies, history of radiation exposure, histopathological type and lab data on the ablation time including serum Tg, serum Anti Tg and thyroid-stimulating hormone (TSH) levels. Results: A total of 34 patients, including 6 males (17.6%) and 28 (82.4%) females with a mean age of 40.8±11.6 years participated in this research. Only vascular invasion had statistically significant P-values less than 0.05, which shows the correlation between ablation success and this factor. Conclusion: This study demonstrated that among different prognostic factors, only vascular invasion had a reverse relationship with ablation success. Other factors did not show statistically significant relashionships with treatment efficiency of DTC.

Keywords

• differentiated thyroid cancer
• dtc prognostic factors
• follicular thyroid
• papillary thyroid