Prevalence of infection <i>H. pylori</i> in Moscow population

Abstract

Aim of investigation. To study the prevalence of H. pylori infection among able-bodied population of Moscow.Material and methods. Diagnostics of Н. pylori infection was implemented at 863 working inhabitants of megacity. Antihelicobacter IgG antibodies were determined in blood serum by immunoenzyme method. In 264 persons with diagnosed Н. pylori infection antiCagA-antibodies were studied. Interview of 634 persons have been taken using original questionnaire by random sample.Results. Extremely high prevalence of infection – 88% was found. Risk factors of infection among population of the town were revealed: age, poor education, bad living conditions (residing at hostel or in shared apartment), absence of the water drain and contact with sewage. No relation of infection prevalence to gender, drinking of non-boiled Moscow tap water and contact with domestic animals was marked.Conclusion. Moscow falls into group of cities with extremely high Н.pylori-infection prevalence, with predominance of virulent bacteria strains. Risk factors of Н. pylori infection in megacity were revealed.

Keywords

• н. pylori infection
• infection prevalence
• anti-н.pylori antibodies
• risk factors
• stomach cancer