Nature Communications (Nov 2016)

The Hippo signalling pathway coordinates organ growth and limits developmental variability by controlling dilp8 expression

  • Emilie Boone,
  • Julien Colombani,
  • Ditte S. Andersen,
  • Pierre Léopold

DOI
https://doi.org/10.1038/ncomms13505
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

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The hormone Dipl8 regulates organ growth inDrosophila whereas the Hippo pathway controls organ size. Here, the authors show that the expression of Dipl8 is regulated by the Hippo pathway, thus linking organ growth or organ size in Drosophila.