Clinical Infection in Practice (Jan 2024)

Kyasanur Forest Disease: Clinical manifestations and molecular dynamics in a zoonotic landscape

  • Amogh Verma,
  • Ayush Anand,
  • Ajeet Singh,
  • Abhinav Khare,
  • Ahmad Neyazi,
  • Sarvesh Rustagi,
  • Neelima Kukreti,
  • Abhay M Gaidhane,
  • Quazi Syed Zahiruddin,
  • Prakasini Satapathy

Journal volume & issue
Vol. 21
p. 100352

Abstract

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The manuscript titled “Kyasanur Forest Disease: Clinical Manifestations and Molecular Dynamics in a Zoonotic Landscape” explores the complexities of Kyasanur Forest Disease (KFD), a tick-borne viral infection caused by the Kyasanur Forest disease virus (KFDV). It delves into the clinical symptoms, transmission dynamics, pathogenesis, and the challenges of diagnosis and treatment, highlighting the disease's prevalence in specific regions of India and its expansion into new areas. The study emphasizes the importance of understanding the molecular structure of KFDV for the development of effective vaccines and therapeutic interventions. It also addresses the global health implications of KFD, underscoring the necessity for interdisciplinary collaboration, early detection, and preventive measures to manage and mitigate the impact of this and similar zoonotic diseases. Through a comprehensive analysis, the paper aims to enhance the scientific community's knowledge on KFD, contributing to global efforts in combating emerging infectious diseases.

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