Clinical and Molecular Allergy (Dec 2022)

Systemic drug-related intertriginous and flexural exanthema-like eruption after Oxford-AstraZeneca COVID-19 vaccine

  • Danilo Di Bona,
  • Andrea Miniello,
  • Eustachio Nettis

DOI
https://doi.org/10.1186/s12948-022-00179-8
Journal volume & issue
Vol. 20, no. 1
pp. 1 – 5

Abstract

Read online

Abstract Systemic drug-related intertriginous and flexural exanthema (SDRIFE) is an adverse drug reaction which manifests as a symmetrical erythematous rash involving the skin folds after systemic drug exposure. A vast array of possible side effects associated with administration of different anti-SARS-CoV-2 vaccines have been reported in literature since the beginning of the COVID-19 pandemic, but only few times SDRIFE-like eruptions have been described in this context. We discuss here a case of SDRIFE-like eruption following the second dose of Oxford-Astrazeneca Vaxzevria vaccine.