Communications Biology (Mar 2022)
Subcellular localization of hippocampal ryanodine receptor 2 and its role in neuronal excitability and memory
- Florian Hiess,
- Jinjing Yao,
- Zhenpeng Song,
- Bo Sun,
- Zizhen Zhang,
- Junting Huang,
- Lina Chen,
- Adam Institoris,
- John Paul Estillore,
- Ruiwu Wang,
- Henk E. D. J. ter Keurs,
- Peter K. Stys,
- Grant R. Gordon,
- Gerald W. Zamponi,
- Anutosh Ganguly,
- S. R. Wayne Chen
Affiliations
- Florian Hiess
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- Jinjing Yao
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- Zhenpeng Song
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- Bo Sun
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- Zizhen Zhang
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- Junting Huang
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- Lina Chen
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- Adam Institoris
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- John Paul Estillore
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- Ruiwu Wang
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- Henk E. D. J. ter Keurs
- Libin Cardiovascular Institute, Department of Cardiovascular Science, Department of Medicine, University of Calgary
- Peter K. Stys
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- Grant R. Gordon
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- Gerald W. Zamponi
- Hotchkiss Brain Institute, Department of Physiology and Pharmacology, University of Calgary
- Anutosh Ganguly
- Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary
- S. R. Wayne Chen
- Libin Cardiovascular Institute, Department of Physiology and Pharmacology, University of Calgary
- DOI
- https://doi.org/10.1038/s42003-022-03124-2
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 16
Abstract
A mouse model containing a GFP-tagged ryanodine receptor 2 (RyR2) has shed light on the precise subcellular localization of hippocampal RyR2 and mechanisms underlying neuronal excitability, learning, and memory.
