International Journal of Rheumatology (Jan 2015)

Prevalence of Hyposalivation in Patients with Systemic Lupus Erythematosus in a Brazilian Subpopulation

  • Cristhiane Almeida Leite,
  • Marcial Francis Galera,
  • Mariano Martínez Espinosa,
  • Paulo Ricardo Teles de Lima,
  • Vander Fernandes,
  • Álvaro Henrique Borges,
  • Eliane Pedra Dias

DOI
https://doi.org/10.1155/2015/730285
Journal volume & issue
Vol. 2015

Abstract

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Background. Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease. Objective. The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated. Methods. This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from 06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance level P27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.