Medicina (Jun 2022)

Diagnostic and Therapeutic Challenges in a Patient with Radiation Retinopathy Complicated by Corticosteroid-Induced Central Serous Chorioretinopathy

  • Michał Chrząszcz,
  • Natalia Mackiewicz,
  • Weronika Pociej-Marciak,
  • Bożena Romanowska-Dixon,
  • Agnieszka Kubicka-Trząska,
  • Maciej Gawęcki,
  • Izabella Karska-Basta

DOI
https://doi.org/10.3390/medicina58070862
Journal volume & issue
Vol. 58, no. 7
p. 862

Abstract

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Central serous chorioretinopathy (CSC) is a common chorioretinal disorder. It has been postulated that impaired retinal pigment epithelium and hyperpermeability of the choriocapillaris may be involved in the development of CSC, but the exact pathomechanism has not been established. We report an unusual case of a middle-aged man who developed CSC after triamcinolone acetonide injection for macular edema. Edema developed as a late complication of radiation retinopathy after brachytherapy for childhood retinoblastoma. Steroid treatment is an important risk factor for CSC, but the underlying causative mechanisms have not been fully elucidated. It is important to increase the awareness of this link among clinicians who prescribe exogenous corticosteroids, irrespective of the route of administration.

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