Clinical features of «metabolism» diseases of the skin in patients with chronic diffuse liver diseases

Abstract

Aim. To determine the clinical features of skin diseases developing in the presence of metabolic disturbances in patients with chronic diffuse liver diseases. Subjects and methods. A total of 368 patients with different clinical forms of hepatopathy were comprehensively examined. Results. 817 cases of seborrhea, skin itch, xerodermia, xanthomatosis, and dyschromia were detected in 318 (86.4%) patients. Conclusion. The prevalence and intensity of cutaneous manifestations depended on the nature of the pathological liver process and indirectly testified to its severity and activity. The symptoms of skin diseases were most pronounced in patients with autoimmune liver lesions, chronic toxic hepatitis, and cirrhosis.

Keywords

• chronic diffuse liver diseases
• skin itch
• seborrhea
• xerodermia
• xanthomatosis
• dyschromia