Veterinarski Glasnik (Jan 2014)

Serological response of piglets vaccinated against swine circovirus infections

  • Stevančević Ognjen,
  • Stojanac Nenad,
  • Potkonjak Aleksandar,
  • Toholj Bojan,
  • Stančić Ivan,
  • Vračar Vuk

DOI
https://doi.org/10.2298/VETGL1404189S
Journal volume & issue
Vol. 68, no. 3-4
pp. 189 – 195

Abstract

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The aim of this research was to determine the influence of immunostimulants to the height of antibody titers specific to PCV2 after vaccination of piglets, based on monitoring the class G antibody titers in piglets and fattening pigs. The experiment was conducted on 60 piglets, divided into two groups of 30 ones each. Both groups were vaccinated on the 21st day of age, and to the second group (group B) immunostimulant was added in food. Three weeks after the vaccination had been performed in the experimental groups, average titer in the population of piglets in group B was 10% higher compared to the average titer in group A, and 7 weeks after the vaccination, average titer values were also higher in group B (EU 1589) compared to group A (1440 EU). Homogeneous immune response and higher average titer values of antibodies against PCV2 after vaccination in group B were probably the result of the use of immuniostimulant containing RNA, nucleotides and nucleotide precursors that are necessary for the synthesis of antibodies.

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