Low-dose Splenic Irradiation in Conjunction With Ruxolitinib to Provide Symptomatic Relief in Heavily Treated, Advanced Stage Myelofibrosis: A Case Series From a UK Tertiary Referral Center

• Alesia Khan,
• Claire Woodley,
• Deepti Radia,
• George N. Mikhaeel,
• Jessica Brady,
• Natalia Curto Garcia,
• Patrick Harrington,
• Jennifer O’Sullivan,
• Shahram Kordasti,
• Yvonne Francis,
• Susan Asirvatham,
• Sahra Ali,
• Priya Sriskandarajah,
• Jamie Saunders,
• Hugues de Lavallade,
• Donal P. McLornan,
• Claire N. Harrison

Affiliations

Alesia Khan

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Claire Woodley

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Deepti Radia

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

George N. Mikhaeel

3 Department of Clinical Oncology, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Jessica Brady

3 Department of Clinical Oncology, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Natalia Curto Garcia

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Patrick Harrington

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Jennifer O’Sullivan

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Shahram Kordasti

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Yvonne Francis

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Susan Asirvatham

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Sahra Ali

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Priya Sriskandarajah

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Jamie Saunders

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Hugues de Lavallade

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Donal P. McLornan

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom

Claire N. Harrison

1 Guy’s International Centre of Excellence in Myeloid Disorders, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom