Pretreatment synthetic magnetic resonance imaging predicts disease progression in nonmetastatic nasopharyngeal carcinoma after intensity modulation radiation therapy

Abstract

Key points 1. SyMRI showed excellent performance in predicting disease progression in NPC. 2. T1_Kurtosis and ADC were independent predictors of progression-free survival. 3. T1_Kurtosis was lower in the non-disease progression group than the disease progression group. 4. Combination of SyMRI, DWI, and clinical factors could improve the predictive performance.

Keywords

• Synthetic magnetic resonance imaging (SyMRI)
• Nasopharyngeal carcinoma (NPC)
• Treatment outcome