Bactericidal and cytotoxic properties of green synthesized nanosilver
               using Rosmarinus officinalis leaves

Daghestani Maha; Al Rashed Sarah A.; Bukhari Wadha; Al-Ojayan Badryah; Ibrahim Eiman M.; Al-Qahtani Asma M.; Merghani Nada M.; Ramadan Rasha; Bhat Ramesa Shafi

doi:10.1515/gps-2020-0025

Green Processing and Synthesis (May 2020)

Bactericidal and cytotoxic properties of green synthesized nanosilver using Rosmarinus officinalis leaves

Daghestani Maha,
Al Rashed Sarah A.,
Bukhari Wadha,
Al-Ojayan Badryah,
Ibrahim Eiman M.,
Al-Qahtani Asma M.,
Merghani Nada M.,
Ramadan Rasha,
Bhat Ramesa Shafi

Affiliations

Daghestani Maha: Zoology Department, Science College, King Saud University, Riyadh, Saudi Arabia
Al Rashed Sarah A.: Department of Botany and Microbiology, College of Science, King Saud University, Riyadh,Saudi Arabia
Bukhari Wadha: Central Laboratory, Female Center for Medical Studies and Scientific Section, King Saud University, Riyadh, KSA, Saudi Arabia
Al-Ojayan Badryah: Central Laboratory, Female Center for Medical Studies and Scientific Section, King Saud University, Riyadh, KSA, Saudi Arabia
Ibrahim Eiman M.: Central Laboratory, Female Center for Medical Studies and Scientific Section, King Saud University, Riyadh, KSA, Saudi Arabia
Al-Qahtani Asma M.: Central Laboratory, Female Center for Medical Studies and Scientific Section, King Saud University, Riyadh, KSA, Saudi Arabia
Merghani Nada M.: Central Laboratory, Female Center for Medical Studies and Scientific Section, King Saud University, Riyadh, KSA, Saudi Arabia
Ramadan Rasha: Central Laboratory, Female Center for Medical Studies and Scientific Section, King Saud University, Riyadh, KSA, Saudi Arabia
Bhat Ramesa Shafi: Department of Botany and Microbiology, College of Science, King Saud University, Riyadh,Saudi Arabia

DOI: https://doi.org/10.1515/gps-2020-0025
Journal volume & issue: Vol. 9, no. 1
pp. 230 – 236

Abstract

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Green synthesized nanoparticles from plant extracts are being used in various biomedical applications, particularly because of their bactericidal and cytotoxic activities. In this study, silver nanoparticles (AgNPs) were successfully synthesized from the Rosmarinus officinalis aqueous leaf extract. Different spectroscopic and microscopic analyses such as ultraviolet-visible (UV-vis) spectroscopy, Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy, and energy-dispersive X-ray spectroscopy were performed to verify the biosynthesized AgNPs in our sample. The formation of nanosilver particles was preliminarily confirmed by UV-vis spectroscopy at 400 nm. The presence of carboxylic or amide groups was confirmed by FTIR, for the reduction of the silver ion. Transmission electron microscopy confirmed a particle size of 12–22 nm. The prepared AgNPs showed good antibacterial activity against human pathogens and good cytotoxic activity against the human breast cancer cell line (MDA MB 231). The nanoparticles prepared from R. officinalis can be used for various biomedical applications.

Published in Green Processing and Synthesis

ISSN: 2191-9542 (Print); 2191-9550 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Science: Chemistry
Website: https://www.degruyter.com/view/j/gps

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