Case Reports in Infectious Diseases (Jan 2023)

A Case Report of Acute Severe Necrotizing Pancreatitis following the Johnson & Johnson Vaccine against the Novel SARS-CoV-2

  • Ayrton I. Bangolo,
  • Mahabuba Akhter,
  • Auda Auda,
  • Rahina Akram,
  • Vignesh K. Nagesh,
  • Donnee Athem,
  • Reenu Thomas,
  • Ligaya Tibalan,
  • Mansi Trivedi,
  • Saima Mushtaq,
  • Neha Singh,
  • Pracheta Bagale,
  • Georgemar V. Arana,
  • Tayyaba Khan,
  • Shelja Sharma,
  • Swetha Mynedi,
  • Dhara D. Patel,
  • Mandeep Saini,
  • Madhurya R. Chinthakuntla,
  • Kareem Ahmed,
  • Mary Gad,
  • Srikara Dheer D. R. Gondhi,
  • Georgemar Arana,
  • Rohini B. Gurumoorthy,
  • Simcha Weissman

DOI
https://doi.org/10.1155/2023/9965435
Journal volume & issue
Vol. 2023

Abstract

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Acute pancreatitis is an inflammatory condition, which is a leading gastrointestinal cause of hospitalization in the United States. Several conditions are associated with acute pancreatitis. More recently, there have been a few cases reported of acute pancreatitis following the Pfizer-BioNTech COVID-19 mRNA vaccine. To our knowledge, no cases of acute pancreatitis have been yet reported following the Johnson & Johnson’s Janssen COVID-19 vaccine (J& J vaccine). Herein we report a 34-year-old male with no significant past medical history admitted with acute necrotizing pancreatitis, the day following the receipt of the J&J vaccine. Based on the Naranjo and the modified Naranjo scale, the patient met the requirements for probable drug induced pancreatitis. This case report has the objective to raise awareness of a potentially severe side effect of the J&J vaccine. We hope to use this case to support screening all patients for previous history of acute pancreatitis before administration of the J& J vaccine.