Current role of non-coding RNAs in the clinical setting

Caterina Vicentini; Francesca Galuppini; Vincenzo Corbo; Matteo Fassan

Non-coding RNA Research (Sep 2019)

Current role of non-coding RNAs in the clinical setting

Caterina Vicentini,
Francesca Galuppini,
Vincenzo Corbo,
Matteo Fassan

Affiliations

Caterina Vicentini: ARC-NET Research Centre, University of Verona, Verona, Italy
Francesca Galuppini: Department of Medicine (DIMED), University of Padua, Padua, PD, Italy
Vincenzo Corbo: ARC-NET Research Centre, University of Verona, Verona, Italy
Matteo Fassan: Department of Medicine (DIMED), University of Padua, Padua, PD, Italy; Corresponding author. Surgical Pathology and Cytopathology Unit - Department of Medicine (DIMED); University of Padua; via Gabelli 61, Padua, 35121, Italy.

Journal volume & issue: Vol. 4, no. 3
pp. 82 – 85

Abstract

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Non-coding RNAs (ncRNAs) have long been considered as “junk” material of the human genome until functional studies have exposed them as critical regulators of gene expression in both physiological and pathological conditions. Mounting evidences have also shown that ncRNAs may serve as diagnostic markers for several disorders, predictor for drugs response, and targets for new therapeutic approaches. In this mini-review, we discuss the state of the art of non-coding RNAs in drug development and their involvement in conventional treatments response. Keywords: miRNAs, Non-coding RNAs, miRNA-based therapy, Drug resistance

Published in Non-coding RNA Research

ISSN: 2468-0540 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Science: Biology (General): Genetics
Website: https://www.keaipublishing.com/en/journals/non-coding-rna-research/

About the journal