In Vitro and In Vivo Comparison of Random versus Site-Specific Conjugation of Bifunctional Chelating Agents to the CD33-Binding Antibody for Use in Alpha- and Beta-Radioimmunotherapy

• Kevin J. H. Allen,
• Connor Frank,
• Rubin Jiao,
• Mackenzie E. Malo,
• Michele Bello,
• Laura De Nardo,
• Laura Meléndez-Alafort,
• Ekaterina Dadachova

Affiliations

Kevin J. H. Allen

College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Connor Frank

College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Rubin Jiao

College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Mackenzie E. Malo

College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Michele Bello

Department of Physics and Astronomy, University of Padua, Padua, Italy

Laura De Nardo

Department of Physics and Astronomy, University of Padua, Padua, Italy

Laura Meléndez-Alafort

Immunology and Molecular Oncology Diagnostics Unit, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy

Ekaterina Dadachova

College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada