On the Concepts and History of Glioblastoma Multiforme - Morphology, Genetics and Epigenetics

Abstract

Glioblastoma multiforme (GBM) is a grade IV WHO malignant tumor with astrocytic differentiation. As one of the most common clinically diagnosed central nervous system (CNS) oncological entries, there have been a wide variety of historical reports of the description and evolution of ideas regarding these tumors.

Keywords

• glioblastoma multiforme
• central nervous system
• oncology
• historical concepts review