Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater

Abstract

Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such experiments can improve understanding of factors associated with norovirus survival in coastal waters and shellfish.

Keywords

• Norovirus
• persistence
• stability
• human intestinal enteroids
• marine environment
• viruses