Archives of Pharmacy Practice (Jan 2016)

Amlodipine-induced reversible gum hypertrophy

  • Gutch Manish,
  • Shakya Shobhit,
  • Kumar Sukriti,
  • Annesh Bhattacharjee,
  • Rao Somendra Singh

DOI
https://doi.org/10.4103/2045-080X.186175
Journal volume & issue
Vol. 7, no. 3
pp. 103 – 105

Abstract

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Gingival hypertrophy is a common manifestation of any pathology affecting gingival and periodontal regions. It commonly follows inflammatory disorders, Vitamin C deficiency, leukemia and due to drugs such as anticonvulsants, immunosuppressants, and calcium channel blockers. Amlodipine is a third generation dihydropyridine derived calcium channel blocker commonly used to treat hypertension. Here, we describe the case of a 45-year-old hypertensive woman who was on amlodipine for 1 year and subsequently developed one of its rarest adverse effects, i.e., gingival hypertrophy.

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