Idiosyncrasies of COVID-19; A Review

Abstract

The Coronavirus disease 2019, identified by Chinese researchers to be the caused by a novel enveloped betacoronavirus, Severe Acute Respiratory Syndrome Coronavirus- 2 which was first isolated in Wuhan, China has been declared a global pandemic by the world health organization. The virus has several structural proteins that contributed to its pathogenesis such as spikes, membrane, envelop and nucleocapsid protein facilitating its attachment, entry and cell-to-cell transmission. The virus is readily transmitted through human-to-human contact and there is presently no approved vaccine for its prevention. This study was carried out to review the epidemiology of Severe Acute Respiratory Syndrome Coronavirus- 2, its host and reservoir, pathogenesis, transmission, clinical manifestation and potential treatment options for the infection.

Keywords

• coronavirus disease 2019
• severe acute respiratory syndrome coronavirus- 2
• structural proteins
• pathogenesis
• epidemiology
• transmission
• hosts and reservoir.