Nature Communications (Aug 2022)

Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage

  • Guangyu Bao,
  • Qiman Gao,
  • Massimo Cau,
  • Nabil Ali-Mohamad,
  • Mitchell Strong,
  • Shuaibing Jiang,
  • Zhen Yang,
  • Amin Valiei,
  • Zhenwei Ma,
  • Marco Amabili,
  • Zu-Hua Gao,
  • Luc Mongeau,
  • Christian Kastrup,
  • Jianyu Li

DOI
https://doi.org/10.1038/s41467-022-32803-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Non‐compressible wounds are a major source of high mortality in trauma victims. Here the authors report on the creation of xerogels impregnated with liquid adhesives which can rapidly absorb fluids promoting blood clotting while forming adhesions to tissue and demonstrate the xerogel in ex vivo and in vivo models.