Nature Communications (Feb 2023)

Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies

  • Delphine Planas,
  • Timothée Bruel,
  • Isabelle Staropoli,
  • Florence Guivel-Benhassine,
  • Françoise Porrot,
  • Piet Maes,
  • Ludivine Grzelak,
  • Matthieu Prot,
  • Said Mougari,
  • Cyril Planchais,
  • Julien Puech,
  • Madelina Saliba,
  • Riwan Sahraoui,
  • Florent Fémy,
  • Nathalie Morel,
  • Jérémy Dufloo,
  • Rafael Sanjuán,
  • Hugo Mouquet,
  • Emmanuel André,
  • Laurent Hocqueloux,
  • Etienne Simon-Loriere,
  • David Veyer,
  • Thierry Prazuck,
  • Hélène Péré,
  • Olivier Schwartz

DOI
https://doi.org/10.1038/s41467-023-36561-6
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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In this work, Planas et al. report that Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 escape neutralization from monoclonal antibodies, and sera from vaccinated individuals with or without Omicron BA.1/2 or BA.5 breakthrough infection.