Urology Case Reports (Nov 2024)

Giant sarcoma of the prostate stroma: Clinical, radiological and histopathological analysis of a rare prostatic cancer

  • Alan de Jesus Martinez Salas,
  • Alfredo Valero-Gomez,
  • Aldo Daniel Jimenez Garcia,
  • Iñigo Navarro-Ruesga,
  • Daniel Calvo-Mena,
  • Stefan Zilli-Hernandez

Journal volume & issue
Vol. 57
p. 102871

Abstract

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Prostate sarcoma is extremely rare, comprising less than 0.1 % of prostate cancers.A 61-year-old male presented to the emergency department with urinary retention and hematuria. Upon resolution of urinary retention, abdominal computed tomography showed a giant prostatic tumor, of approximately 1700 cubic centimeters, causing bilateral ureteric obstruction, and invasion of rectum and sigmoid colon. Laparotomy due to bowel obstruction showed peritoneal carcinomatosis. Palliative chemotherapy was initiated; however, he died due to hematological toxicity related to doxorubicin.Radical surgery is the ideal treatment; in cases of advanced or metastatic disease, adjuvant or palliative chemotherapy or radiotherapy withholds little or no benefit.

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