Canadian Journal of Gastroenterology (Jan 2006)
The Association of Helicobacter pylori Infection and Nonsteroidal Anti-Inflammatory Drugs in Peptic Ulcer Disease
Abstract
BACKGROUND AND AIM: Peptic ulcer disease (PUD) affects 10% of the world population. Helicobacter pylori infection and the use of a nonsteroidal anti-inflammatory drug (NSAID) are the principal factors associated with PUD. The aim of the present study was to evaluate a cohort of patients with PUD and determine the association between H pylori infection and NSAID use.