Clinical Case Reports (Apr 2024)
Antimicrobial‐associated encephalopathy due to ampicillin
Abstract
Key Clinical Message Because the β‐lactam ring has a molecular structure similar to that of gamma‐aminobutyric acid (GABA) neurotransmitters, it binds to GABA A receptors and inhibits GABAergic transmission, causing AAE. The possibility of antimicrobial‐associated encephalopathy should be considered in cases of neurological or psychiatric symptoms after initiating an antimicrobial regimen.
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