Clinical Case Reports (Apr 2024)

Antimicrobial‐associated encephalopathy due to ampicillin

  • Naoya Mizutani,
  • Tsuneaki Kenzaka

DOI
https://doi.org/10.1002/ccr3.8665
Journal volume & issue
Vol. 12, no. 4
pp. n/a – n/a

Abstract

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Key Clinical Message Because the β‐lactam ring has a molecular structure similar to that of gamma‐aminobutyric acid (GABA) neurotransmitters, it binds to GABA A receptors and inhibits GABAergic transmission, causing AAE. The possibility of antimicrobial‐associated encephalopathy should be considered in cases of neurological or psychiatric symptoms after initiating an antimicrobial regimen.

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