Repetitive transcranial magnetic stimulation for major depression and obsessive-compulsive disorders in Singapore

Abstract

Repetitive transcranial magnetic stimulation (rTMS) is a novel and noninvasive neuromodulation therapy used for treatment-resistant major depressive disorder (MDD)1 and obsessive-compulsive disorder (OCD).2 OCD and depression are disabling psychiatric disorders, which have a detrimental impact on individuals, their families and society.3,4 The lifetime prevalence of depression is high at 5.8% and OCD affects 1 in 28 Singaporeans.5 Depression contributes substantially to the global burden of disease and disability.6 However, despite effective pharmacological and psychological interventions, approximately 40% to 50% of patients have not responded satisfactorily to standard treatment.7