Etoposide-induced apoptosis in murine neuroblastoma (N2A) cells infected with Paramyxoviruses

Abstract

The present study aimed to determine whether measles virus can induce apoptosis in murine neuroblastoma cells and the behavior of these cells under acute infection with measles virus or persistent infection with canine distemper virus upon treatment with etoposide. Measles virus induced necrosis in murine neuroblastoma cells. Canine distemper virus-persistent infection did not alter murine neuroblastoma cells behavior when treated with etoposide.

Keywords

• apoptosis
• measles virus
• canine distemper virus
• murine neuroblastoma cells