Severe neurotoxicity due to cefepime in a kidney transplanted patient: case report

Abstract

Cefepime is a betalactamic antibiotic used for the treatment of patients with severe infections. It is mainly excreted by the kidney, so that its half-life is significantly increased in patients with kidney failure, and in this population adverse effects may be more severe including neurotoxicity. We report the case of a kidney-transplanted patient who presented neurotoxicity associated with the use of cefepime.

Keywords

• Cephalosporins
• Kidney Transplantation
• Neurotoxicity Syndromes
• Cefalosporinas
• Síndrome de Neurotoxicidad
• Trasplante de Riñón
• Síndrome de Neurotoxicidade
• Transplante de Rim