Inactivation of CACNA1H induces cell apoptosis by initiating endoplasmic reticulum stress in glioma

Liu Sheng; Ba Ying; Li Chenglong; Xu Guangming

doi:10.1515/tnsci-2022-0285

Translational Neuroscience (May 2023)

Inactivation of CACNA1H induces cell apoptosis by initiating endoplasmic reticulum stress in glioma

Liu Sheng,
Ba Ying,
Li Chenglong,
Xu Guangming

Affiliations

Liu Sheng: Department of Neurosurgery, Binzhou Medical University Hospital, Binzhou, 256603, China
Ba Ying: Department of Gastroenterology, Binzhou Medical University Hospital, Binzhou, 256603, China
Li Chenglong: Department of Neurosurgery, Binzhou Medical University Hospital, Binzhou, 256603, China
Xu Guangming: Department of Neurosurgery, Shandong Provincial Hospital, Shandong University, No. 324, Jingwuweiqi Road, Jinan, 250021, China

DOI: https://doi.org/10.1515/tnsci-2022-0285
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 12

Abstract

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Ca2+ channels are abnormally expressed in various tumor cells and are involved in the progression of human glioma. Here, we explored the role of a calcium channel, voltage-dependent, T-type, alpha 1H subunit (CACNA1H), which encodes T-type Ca2+ channel Cav3.2 in glioma cells.

Published in Translational Neuroscience

ISSN: 2081-6936 (Online)
Publisher: De Gruyter
Country of publisher: Poland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.degruyter.com/view/j/tnsci

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Abstract

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