EFFICIENCY OF USING TUBERCULOUS RECOMBINANT ALLERGEN FOR SCREENING FOR TUBERCULOUS INFECTION IN CHILDREN AND ADOLESCENTS IN STAVROPOL KRAY

Abstract

Goal of the study: to define efficiency ofthe screening with the tuberculous recombinant allergen (TRA) in children and adolescents with the purpose of tuberculosis detection and defining the groups of the advanced risk of developing tuberculosis.Materials and methods. Efficiency ofscreening fortuberculosis was compared upon the results ofskin tests withTRA in 72,601 children and Mantoux test with 2 TU PPD-L in 99,448 children in the age from 1 to 14 years old.Results. The frequency of tuberculosis detection in the mass screening with TRA among children made 0.4 per 1000 of those examined, among adolescents it made 0.7 per 1000 of those examined which was significantly and confidently higher compared to the screening with Mantoux test. The use of TRA test allowed reducing more than 5 times the number of candidates for preventive chemotherapy under direct observation ofthe drug intake.

Keywords

• туберкулез
• дети
• подростки
• диаскинтест
• проба манту
• аллерген туберкулезный рекомбинантный