The invisible threat: A 30-year review of air pollution's impact on diarrhoea from the global burden of disease study 2021

Changhao Zhang; Kaiqi Yang; Yang Yu; Haoxi Liu; Yijun Chen; Jiaxuan Zuo; Minyue Yin; Yuchen Ding; Jinlong Chen; Xiujing Sun; Shutian Zhang

Ecotoxicology and Environmental Safety (Feb 2025)

The invisible threat: A 30-year review of air pollution's impact on diarrhoea from the global burden of disease study 2021

Changhao Zhang,
Kaiqi Yang,
Yang Yu,
Haoxi Liu,
Yijun Chen,
Jiaxuan Zuo,
Minyue Yin,
Yuchen Ding,
Jinlong Chen,
Xiujing Sun,
Shutian Zhang

Affiliations

Changhao Zhang: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Kaiqi Yang: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Yang Yu: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Haoxi Liu: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Yijun Chen: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Jiaxuan Zuo: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Minyue Yin: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Yuchen Ding: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Jinlong Chen: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Xiujing Sun: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China
Shutian Zhang: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China; National Clinical Research Center for Digestive Diseases, Beijing 100050, China; State Key Laboratory of Digestive Health, Beijing 100050, China; Beijing Digestive Disease Center, Beijing 100050, China; Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing 100050, China; Corresponding author at: Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

Journal volume & issue: Vol. 291
p. 117771

Abstract

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Background: Diarrhoea remains a major contributor to global morbidity and mortality among children younger than 5 years. This study aims to provide an updated assessment of diarrhoea deaths and disability-adjusted life years (DALYs) attributable to air pollution from 1990 to 2021. Methods: The deaths and DALYs data for diarrhoea attributable to air pollution were derived from the 2021 Global Burden of Diseases Study (GBD). Age-standardized rates (ASRs) and estimated annual percentage changes (EAPCs) were used to assess trends in deaths related to diarrhoea. In addition, Auto-Regressive Integrated Moving Average (ARIMA) and Ensemble Smoothing (ES) models were used to predict the epidemic trends of diarrhoea from 2022 to 2046, and frontier analysis was conducted to explore the potential reduction in the burden of diarrhoea in different regions. Results: Globally, from 1990 to 2021, there were 45,851 deaths from diarrhoea attributable to air pollution (95 % uncertainty interval [UI], 32,228–56,815) in 1990, and 6559 deaths (95 % UI, 4931 to 9245) in 2021. In total, diarrhoea attributable to air pollution was responsible for 4134,309 DALYs (95 % UI, 1073,440 to 1277,490) in 1990, and 593,960 DALYs (95 % UI, 446,774 to 835,347) in 2021. The decreasing trend of diarrhoea burden is uneven in different countries and regions, with higher diarrhoea deaths and DALYs in low and low-middle SDI regions, while relatively lower in high SDI regions. Predictive analysis suggests that by 2046, deaths and DALYs of air pollution-related diarrhoea, as well as their corresponding ASR, will continue to decrease. Conclusion: Although the global burden of diarrhoea caused by air pollution has decreased in the past 30 years, it remains an important public health issue in low and low-middle SDI regions. The research findings emphasize the importance of public health policies and planning in reducing deaths related to diarrhoea and the disease burden, and point out the need for more targeted prevention strategies in order to reduce the disease burden.

Published in Ecotoxicology and Environmental Safety

ISSN: 0147-6513 (Print); 1090-2414 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Technology: Environmental technology. Sanitary engineering: Environmental pollution; Geography. Anthropology. Recreation: Environmental sciences
Website: https://www.journals.elsevier.com/ecotoxicology-and-environmental-safety

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