Mesenchymal stromal cell-derived small extracellular vesicles modulate macrophage polarization and enhance angio-osteogenesis to promote bone healing

• Shang Jiunn Chuah,
• Chee Weng Yong,
• Kristeen Ye Wen Teo,
• Jacob Ren Jie Chew,
• Yi Ann Cheow,
• Shipin Zhang,
• Raymond Chung Wen Wong,
• Asher Ah Tong Lim,
• Sai Kiang Lim,
• Wei Seong Toh

Affiliations

Shang Jiunn Chuah

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Chee Weng Yong

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Kristeen Ye Wen Teo

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Jacob Ren Jie Chew

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Yi Ann Cheow

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Shipin Zhang

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Raymond Chung Wen Wong

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Asher Ah Tong Lim

Faculty of Dentistry, National University of Singapore, 119085, Singapore

Sai Kiang Lim

Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, 138648, Singapore

Wei Seong Toh

Faculty of Dentistry, National University of Singapore, 119085, Singapore; Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 119288, Singapore; Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, 117583, Singapore; Tissue Engineering Program, Life Sciences Institute, National University of Singapore, 117456, Singapore; Integrative Sciences and Engineering Program, NUS Graduate School, National University of Singapore, 119077, Singapore; Corresponding author. Faculty of Dentistry, National University of Singapore, 119085, Singapore.