Dressler Syndrome

Abstract

Dressler syndrome is a form of pericarditis arising from acute injury to the myocardium or pericardium. It manifests within the tenth week post-infarction. It is noteworthy that the myocardial injury preceding the syndrome may result from cardiotomy. Thus, while the general focus is post-infarction, sources also refer to post-cardiotomy syndrome. Its pathophysiology remains uncertain, potentially involving an interaction between the complement system and affected tissue. To date, no pathognomonic signs or consensus criteria exist, posing a substantial challenge for clinicians. Diagnosis necessitates a history of myocardial or pericardial injury, in conjunction with inflammatory markers and electrocardiographic abnormalities; imaging aids in ruling out differentials and complications. Treatment is tailored based on hemodynamic stability and comorbidities. Acquaintance with this syndrome is crucial, as though it often follows a self-limiting course, a high recurrence rate impairs patients’ quality of life.

Keywords

• myocardial infarction
• pericarditis
• postpericardiotomy syndrome
• inflammation