Nature Communications (Jan 2020)

An electrochemical biosensor for the detection of epithelial-mesenchymal transition

  • Xin Du,
  • Zhenhua Zhang,
  • Xiaodi Zheng,
  • Hongyan Zhang,
  • Dan Dong,
  • Zhenguo Zhang,
  • Min Liu,
  • Jun Zhou

DOI
https://doi.org/10.1038/s41467-019-14037-w
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

Read online

Epithelial-mesenchymal transition (EMT) plays a key role in embryonic development, wound healing and cancer. Here the authors develop an electrochemical sensor to detect EMT using E-cadherin antibody-quantum dot conjugates and a carbon nanotube-gold nanoparticle-modified electrode as a detection platform.