Лечащий Врач (Oct 2022)

The treatment of chronic cystitis with combination with papillomavirus infection and urogenital herpes 1 and 2

  • E. V. Tkachenko,
  • P. I. Nekrasov

DOI
https://doi.org/10.51793/OS.2022.25.9.004
Journal volume & issue
Vol. 0, no. 9
pp. 24 – 30

Abstract

Read online

Cystitis is not only a frequent and repeatedly relapsing disease, but also a socially significant disease that significantly worsens the patient's quality of life. In practical work, we quite often met patients with such pronounced dysuric phenomena and hematuria that a sick leave certificate was required for the course of treatment. The article analyzes the results of treatment of 96 patients diagnosed with chronic cystitis with concomitant diagnoses of papillomavirus infection (human papillomavirus) and urogenital herpes (herpes simplex virus) types 1 and 2. The aim of the work was to evaluate the effectiveness of complex therapy for acute or chronic cystitis. 40 patients suffering from chronic cystitis on the background of herpetic viral infection and 50 patients with chronic cystitis on the background of human papillomavirus infection were treated. The prescription of drugs for the treatment of a chronic inflammatory process in the bladder was carried out in accordance with the Russian clinical guidelines of 2016. Patients received antibacterial therapy with Furamag 50, and alternative drugs Ciprofloxacin 500 and Levofloxacin 500 were used. When a herpes viral infection was detected, we used the antiviral drug Acyclovir 200 In case of detection of papillomavirus infection, Isoprinosine 500 was prescribed. In the treatment of patients in both groups, the immunomodulator Tubosan 200 mg was used. As a result of the therapy, the patients achieved remission of chronic cystitis or its complete cure, confirmed by clinical and laboratory data. At the end of treatment, a decrease or complete absence of the viral load of human papillomavirus and herpes simplex virus was also observed. No significant side effects were noted during treatment. Thus, Tubosan can be used as an immunotropic agent in the complex therapy of acute and chronic cystitis to improve the outcome of treatment.

Keywords