Dermatology Practical & Conceptual (Feb 2022)

Topical and Conventional Systemic Treatments in Atopic Dermatitis: Have They Gone Out of Fashion?

  • Giulia Calabrese,
  • Gaetano Licata,
  • Alessio Gambardella,
  • Alina De Rosa,
  • Roberto Alfano,
  • Giuseppe Argenziano

DOI
https://doi.org/10.5826/dpc.1201a155

Abstract

Read online

Atopic dermatitis is a Th2 disease, due to relapse of IL-4 and IL-13 by Th2 cells. Despite the approval by FDA of dupilumab, the first monoclonal antibody for the severe forms, traditional drugs remain a milestone for the treatment of this dermatosis. Dermatologists need a good knowledge of all therapies for an integrated and personalized management of patients.

Keywords