Communications Biology (May 2022)

Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients

  • Diego Cantoni,
  • Martin Mayora-Neto,
  • Nazia Thakur,
  • Ahmed M. E. Elrefaey,
  • Joseph Newman,
  • Sneha Vishwanath,
  • Angalee Nadesalingam,
  • Andrew Chan,
  • Peter Smith,
  • Javier Castillo-Olivares,
  • Helen Baxendale,
  • Bryan Charleston,
  • Jonathan Heeney,
  • Dalan Bailey,
  • Nigel Temperton

DOI
https://doi.org/10.1038/s42003-022-03325-9
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 8

Abstract

Read online

Bat Coronavirus RaTG13, a sarbecovirus related to SARS-CoV-2, is more potently neutralized by antibodies from convalescent SARS-CoV-2-infected patients as well as vaccinated healthcare workers despite the spike proteins having high diversity within their receptor binding domains (RBD).