Children (Jan 2024)

Managing Pediatric Asthma Exacerbations: The Role of Timely Systemic Corticosteroid Administration in Emergency Care Settings—A Multicentric Retrospective Study

  • Luna Antonino,
  • Eva Goossens,
  • Josefien van Olmen,
  • An Bael,
  • Johan Hellinckx,
  • Isabelle Van Ussel,
  • An Wouters,
  • Tijl Jonckheer,
  • Tine Martens,
  • Sascha Van Nuijs,
  • Carolin Van Rossem,
  • Yentl Driesen,
  • Nathalie Jouret,
  • Eva Ter Haar,
  • Sabine Rozenberg,
  • Els Vanderschaeghe,
  • Susanne van Steijn,
  • Stijn Verhulst,
  • Kim Van Hoorenbeeck

DOI
https://doi.org/10.3390/children11020164
Journal volume & issue
Vol. 11, no. 2
p. 164

Abstract

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Background: Asthma is the most prevalent chronic respiratory condition in children. An asthma exacerbation (AE) is a frequent reason for emergency department (ED) visits. An important step in the management of a moderate to severe AE is the administration of systemic corticosteroids (SCS) within 1 h after ED presentation. This study aimed to determine the timing of SCS administration and correlate this with the length of stay and oxygen therapy duration and to explore factors predicting timely administration. Methods: This study used a retrospective multicenter observational design based on electronic medical records review. Children aged 1 92–Q3 380). A correlation was found between timing and oxygen treatment duration (r = 0.363, p p < 0.001). No patient characteristics predicted timely SCS administration. Conclusions: Three in four children who presented with a moderate to severe AE at the ED did not receive SCS within the first hour. A prolonged timing of SCS administration correlated with a prolonged length of stay and extended need for oxygen support.

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