Managing Pediatric Asthma Exacerbations: The Role of Timely Systemic Corticosteroid Administration in Emergency Care Settings—A Multicentric Retrospective Study
Luna Antonino,
Eva Goossens,
Josefien van Olmen,
An Bael,
Johan Hellinckx,
Isabelle Van Ussel,
An Wouters,
Tijl Jonckheer,
Tine Martens,
Sascha Van Nuijs,
Carolin Van Rossem,
Yentl Driesen,
Nathalie Jouret,
Eva Ter Haar,
Sabine Rozenberg,
Els Vanderschaeghe,
Susanne van Steijn,
Stijn Verhulst,
Kim Van Hoorenbeeck
Affiliations
Luna Antonino
Laboratory of Experimental Medicine and Pediatrics, Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium
Eva Goossens
Centre for Research and Innovation in Care, Department of Nursing Science and Midwifery, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium
Josefien van Olmen
Department of Family Medicine and Population Health, University of Antwerp, 2610 Antwerp, Belgium
An Bael
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Johan Hellinckx
Department of Pediatrics, General Hospital Klina (AZ Klina), 2930 Brasschaat, Belgium
Isabelle Van Ussel
Department of Pediatrics, General Hospital Voorkempen (AZ Voorkempen), 2390 Malle, Belgium
An Wouters
Department of Pediatrics, General Hospital Voorkempen (AZ Voorkempen), 2390 Malle, Belgium
Tijl Jonckheer
Department of Pediatrics, GasthuisZusters Antwerp, 2610 Antwerp, Belgium
Tine Martens
Department of Pediatrics, GasthuisZusters Antwerp, 2610 Antwerp, Belgium
Sascha Van Nuijs
Department of Pediatrics, GasthuisZusters Antwerp, 2610 Antwerp, Belgium
Carolin Van Rossem
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Yentl Driesen
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Nathalie Jouret
Department of Pediatric Pulmonology, Antwerp University Hospital, 2610 Antwerp, Belgium
Eva Ter Haar
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Sabine Rozenberg
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Els Vanderschaeghe
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Susanne van Steijn
Department of Pediatric Pulmonology, Hospital Network Antwerp, 2020 Antwerp, Belgium
Stijn Verhulst
Laboratory of Experimental Medicine and Pediatrics, Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium
Kim Van Hoorenbeeck
Laboratory of Experimental Medicine and Pediatrics, Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp, 2610 Antwerp, Belgium
Background: Asthma is the most prevalent chronic respiratory condition in children. An asthma exacerbation (AE) is a frequent reason for emergency department (ED) visits. An important step in the management of a moderate to severe AE is the administration of systemic corticosteroids (SCS) within 1 h after ED presentation. This study aimed to determine the timing of SCS administration and correlate this with the length of stay and oxygen therapy duration and to explore factors predicting timely administration. Methods: This study used a retrospective multicenter observational design based on electronic medical records review. Children aged 1 92–Q3 380). A correlation was found between timing and oxygen treatment duration (r = 0.363, p p < 0.001). No patient characteristics predicted timely SCS administration. Conclusions: Three in four children who presented with a moderate to severe AE at the ED did not receive SCS within the first hour. A prolonged timing of SCS administration correlated with a prolonged length of stay and extended need for oxygen support.